Month: January 2020
Their names
Tiffany Enriquez, served seven years with the Honolulu Police Department
Kaulike Kalama, served nine years with the Honolulu Police Department
Innocent victims
- Mojtaba Abbasnezhad, a student at the University of Toronto
- Mehran Abtahi, a postdoctoral research fellow
- Iman Aghabali, PhD student
- Evin Arsalani, 30, had travelled to Iran to attend a wedding with her husband, Hiva Molani, 38, and their one-year-old daughter Kurdia
- Ghanimat Azhdari, a PhD student promoting the rights of indigenous groups, “cherished and loved”
- Samira Bashiri, a researcher married to Hamid Kokab Setareh, a PhD student
- Mohammad Amin Beiruti, a student at the University of Toronto
- Shekoufeh Choupannejad, obstetrician, mother of Saba Saadat and Sara
- Delaram Dadashnejad, an international student studying nutrition at a college in Vancouver
- Mojgan Daneshmand, married to Pedram Mousav, taught engineering at the University of Alberta
- Daria, 14, daughter
- Ali Dolatabadi, an engineering professor at Concordia University who would become Siavash’s thesis supervisor
- Dorina, 9, daughter
- Niloufar Ebrahim, married
- Parisa Eghbalian, mother to Reera Esmaeilion
- Mohammad Mahdi Elyasi, studied mechanical engineering and graduated in 2017
- Mansour Esnaashary Esfahani, PhD student at the University of Waterloo
- Mehdi Eshaghian, PhD student
- Reera Esmaeilion, daughter to Parisa Eghbalian
- Siavash Maghsoudlou Estarabadi, former postdoctoral researcher
- Sharieh Faghihi, dentist
- Aida Farzaneh, wife to her husband Arvin Morattab
- Marzieh Foroutan, “Mari”, PhD student at the University of Waterloo
- Volodymyr Gaponenko, Captain
- Iman Ghaderpanah, coupled with
- Parinaz Ghaderpanah, volunteers with an Iranian cultural charity
- Siavash Ghafouri-Azar, engineer, returning home with his new wife, Sara Mamani, “He has been a very positive and passionate from childhood until his soul’s departure from his body. Rest in peace my dearest side by your beloved wife”
- Amirhossein Ghassemi, a graduate student studying biomedical engineering (“I can’t use past tense. I think he’s coming back. We play again. We talk again. It’s too difficult to use past tense, too difficult. No one can believe it,”)
- Mahdieh Ghassemi, mother to Arsan Niazi and Arnica Niazi
- Mandieh Ghavi, sister to Masoumeh Ghavi
- Masoumeh Ghavi, sister of Mandieh Ghavi
- Amirhossein Bahabadi Ghorbani, 21, studying science at the University of Manitoba and hoped to become a doctor
- Pouneh Gourji, 25, a graduate student in computer science at the university, and had gone to Iran for to wed Arash Pourzarabi, 26
- Bahareh Hajesfandiari, wife to Mohammad Mahdi Sadeghi, daughter to Anisa Sadeghi, a family from Winnipeg
- Ardalan Ebnoddin Hamidi, from a family of three from Vancouver were returning from Iran where they had taken a short vacation and were confirmed to have been on the flight
- Hadis Hayatdavoudi, student
- Mohammad Amin Jebelli, a student at the University of Toronto
- Kamyar, teenage son from a family of three from Vancouver were returning from Iran where they had taken a short vacation and were confirmed to have been on the flight
- Forough Khadem, described “as a promising scientist and a dear friend”
- Serhii Khomenko, First Officer
- Kurdia, 1, daughter to Evin Arsalani, 30, and Hiva Molani, 38
- Mohammad Asadi Lari, co-founder of a youth-run charity that helps students in mathematics and science, and
- Zeynab Asadi Lari, “She was full of dreams, and now they’re gone”
- Denys Lykhno, flight attendant
- Firouzeh Madani, a couple with Naser Pourshaban Oshibi
- Fatemeh Mahmoodi, graduate student
- Maryam Malek, graduate student
- Sara Mamani, returning home with her husband Siavash Ghafouri-Azar, couple recently bought their first home
- Ihor Matkov, was flight PS752’s chief attendant
- Mohammad Moeini, from Quebec
- Hiva Molani, 38, had travelled to Iran to attend a wedding with his wife, Evin Arsalani, 30, and their one-year-old daughter Kurdia
- Arvin Morattab, twin said “he said he was coming back home soon”, husband to his wife Aida Farzaneh
- Pedram Mousavi, married to Mojgan Daneshmand, taught engineering at the University of Alberta
- Mariia Mykytiuk, 24, flight attendant
- Elnaz Nabiyi
- Farzaneh Naderi, a customer service manager at Walmart, mother to Noojan Sadr
- Milad Nahavandi, student
- Oleksiy Naumkin, instructor
- Arsan Niazi, daughter of Mahdieh Ghassemi, sister to
- Arnica Niazi, daughter of Mahdieh Ghassemi, sister to Arsan Niazi
- Ghazal Nourian, student
- Naser Pourshaban Oshibi, a couple with Firouzeh Madani
- Valeriia Ovcharuk, 28, flight attendant
- Arash Pourzarabi, 26, a graduate student in computer science at the university, and had gone to Iran for to wed Pouneh Gourji, 25
- Nasim Rahmanifar
- Niloofar Razzaghi from a family of three from Vancouver were returning from Iran where they had taken a short vacation and were confirmed to have been on the flight.
- Saba Saadat, studying medicine at the University of Alberta
- Kasra Saati, an aircraft mechanic
- Anisa Sadeghi, daughter to Bahareh Hajesfandiari, daughter to Mohammad Mahdi Sadeghi, a family from Winnipeg
- Mohammad Mahdi Sadeghi, husband to Bahareh Hajesfandiari, father to Anisa Sadeghi, a family from Winnipeg
- Noojan Sadr, 11, son of Farzaneh Naderi
- Amir Saeedinia
- Mohammad Salehe, a student at the University of Toronto, “he was a bit reserved and shy but a brilliant computer programmer whose talent was widely recognized”
- Sara, recently graduated the University of Alberta
- Sajedeh Saraeian, student
- Hamid Kokab Setareh, PhD student married to Samira Bashiri, a researcher
- Yuliia Solohub, flight attendant
- Kateryna Statnik, flight attendant
- Saeed Tahmasebi, engineer living in Dartford
- Afifa Tarbhai, mother to
- Alina Tarbhai, employed by the Ontario Secondary School Teacher’s Federation (OSSTF)
- Mohammed Reza Kadkhoda Zadeh, owned a dry cleaners in West Sussex
- Sam Zokaei, engineer from Twickenham
I have no information on the 82 Iranian nationals. I have no information on the 10 Swedish nationals.
Source of information: https://www.bbc.com/news/world-middle-east-51032823
A new liberalism 3
How do I know the moral arc of history bends toward justice? Because the American people will put their back into it. As they have from Selma to Montgomery, from Earthrise to Seneca Falls, in DC at times. Justice is not always timely nor guaranteed. But it can be worked very hard for. And as that people greatest in liberty – or to such heights we should climb, from such vantages view – I think we ought to work very hard for the ever greater justice, the ever minimized injustice, the steady pursuit of truth. At times this will be a struggle. But again and again I find my fellow compatriots ready to resume that struggle. Ready to put their back into it. The noble life of the good citizen of The Great Society is bettered by the continued, honest, and plain pursuit of justice for all. The ever greater nation requires a people pushing toward ever greater mercy, understanding, peace.
BIOMEDE 211, Circuits and Systems in Biomedical Engineering
Course description (from ABET course profile)
Course description (in other terms)
Instructors
Requirements
Previous/Concurrent coursework
Textbook
A well-maintained notebook
Access to the internet regularly
Assessments
- Homework I on foundational electrical physics with special application within the biomedical realm (Jan 22, 100 points)
- Homework II on basic circuit analysis for arbitrary planar circuits using passive components (Feb 5, 100 points)
- Homework III on circuit analysis using active components with transformations (Feb 19, 100 points)
- Exam I on synthesizing knowledge of circuits to analyze arbitrary active circuits with special reference to biomedical applications (Feb 24, 300 points)
- Lab I on using basic laboratory equipment and constructing simple circuits on breadboards (by Feb 26, 100 points, team-based); teams will be randomly assigned and a group notebook describing laboratory activities will be collected
- Homework IV on the application of the Laplace transform to ordinary differential equations (Mar 18, 100 points)
- Homework V on system convolution, response, and design (Apr 1, 100 points)
- Homework VI on the acquisition of bioelectrical signals (Apr 15, 100 points)
- Lab II on the design of a biopotential amplifier (by Apr 22, 100 points, team-based); teams will be randomly assigned and a group notebook describing laboratory activities will be collected
- Class participation via one set of lecture notes which may either be neatly written by hand, typeset, and/or a revision of the set of notes available (by Apr 22, 100 points)
- Exam II on the application of electricals circuits to interface with biomedical systems (Apr 24, 300 points)
Policies
Late Policy
Sickness, Health Policy
Exam Policy
Honor Code
Contact
- Stop by my office, 2130 LBME, if I’m in my office, I will almost always talk to you;
- Call my office phone, 734-647-8638, if I’m in my office, I will almost always answer it;
- Talk to me before or after class or in the hallway, but make sure I write it down;
- Send me an email through Canvas (within 1 business day); and
- Send me an email to my email address, belmont@umich.edu (within 3-5 business days).
New and Experimental Features
Laboratory Modules
- In the first module, you will learn the basics of electronic laboratory equipment (function generators, oscilloscopes, data acquisition) and how to construct simple, yet useful circuits. A simple narrative summary of what was done in lab, including measurements, speculation, and suggestions for improvement, will be gathered using a shared electronic notebook.
- In the second module, you will design a basic biopotential amplifier with a frequency response tailored to a specific biomedical signal. Passive and active versions of a filter will be made, measured, and refined. A simple narrative summary of what was done in lab, including measurements, speculation, and suggestions for improvement, will be gathered using a shared electronic notebook.
Class Notes
BIOMEDE 458 / EECS 458, Biomedical Instrumentation
Course description
From ABET course profile
From your instructor’s heart
Instructors
Requirements
Previous/Concurrent Coursework
Regular Access to the Internet
Intended outline of the class
- A share-out, 16 days after starting the module;
- A group-notebook, 21 days after starting the module;
- A peer review and self-reflection, 22 days after starting the module; and
- A formal laboratory report, 28 days after starting the module.
Assignments
- The Big List of Medical Devices. Six concise descriptions (100-300 words) of medical devices submitted to Canvas on Jan 23, Feb 6, Feb 20, Mar 12, Mar 26, and Apr 9 by 9:00 a.m. EST. Each submission is worth 0.5% of one’s total grade (and is based on completeness). Once during the semester, one will participate in a small group discussion regarding a medical device of one’s choosing. Doing so is worth 2% of one’s total grade. Put differently, 0.5% x 6 + 2% = 5% overall. Individual assignments.
- Must be a short summary (100–300 words) on a unique medical device (i.e., one that has not be previously written about
- Always due Wednesdays by 9:00 a.m. EST
- Due generally every other week
- Once a semester discussion with others about a device
- Readings. The past and future histories of medical devices are written down in many areas. I have selected 72 readings, amounting to a whopping 2,400 pages of written material. Several of those pages include figures, tables, indices, practice problems, physiology, instrumentation, legislation, regulation, and ethical conceit. Once during the semester you will be required to give a short summary presentation of one of these in front of your peers (or an equivalent beforehand). Please prepare, approximately 15-20 minutes worth of audiovisual explanation of the reading. Presentation of such a summary is 5% of one’s grade and a copy of audiovisual aids must be submitted to Canvas by the time of one’s presentation. A list of the readings can be seen herein.
- Interviews. Five entwined assignments, each worth 1% x 5 = 5% overall:
- Submit reading for consideration by Feb 26. Find some article somewhere about medical devices that made you think. These will be shared with the whole class, so make sure they’re interesting.
- Submit questions beforehand by Feb 26. Given that you have read at least one interesting thing about medical devices, submit at least five questions it made you ask about biomedical devices (especially instrumentation).
- Interview a biomedical professional by Mar 18. Given that the class has submitted many questions about medical devices based on background readings, go ask a medical professional some of the ones that most interest you. There are four main categories we are interested here: laws, businesses, regulations, and consequences. That said, make what you want of your interview.
- Moderate a discussion in class by Apr 8. Report out your interview to others in the class. Sharing your experiences in both small group and class-wide settings.
- Participate in a discussion in class by Apr 8. Listen to a peer report out their discussion with a medical professional on a topic.
- Homework. A single assignment designed to assess the individual instrumentation wherewithal will be due Mar 11. An exploration of topics covered in the class will be evaluated. The assignment is worth 5% of one’s grade.
- Laboratory Share-Outs. At the end of each laboratory module (Jan 30, Feb 20, Mar 26, Apr 21), teams will present their work and results to their peers for review, encouragement, and improvement. Tough questions will be posed and experiences shared. 5% each, 5% x 4 = 20% overall
- Notebooks. A group notebook demonstration good documentation practices will be collected via Canvas Feb 4, Feb 25, Mar 31, and Apr 24 by 9:00 a.m. EST. The notebook will be created via Lab Archives. 5% each module, 5% x 4 = 20% overall
- Review and Reflections. A little while after the end of each module (Feb 5, Feb 26, Apr 1, Apr 24), one will be given an opportunity to reflect on one’s learning and review one’s peer’s laboratory behavior. The review from one’s peers will be worth 3% each module, the self-reflection each worth 2%. That is, (3% + 2%) x 4 = 20% overall
- Laboratory Manuals. A brief formal write-up of the experiments conduct at one of two levels: K–12 (i.e., to less experience audiences) or university (i.e., to one’s peers). Each module 5% x 4 = 20% overall due Feb 18, Mar 10, Apr 7, Apr 24.
- Proposal(s). Ungraded periods in which one (1) brainstorms with one’s peers to propose medical instruments we are excited to create on Feb 25 and (2) selects a team and a project to work with and on for the remainder of the semester by Feb 27. Projects will be limited in budget and at the discretion of the instructor (mostly so they remain doable in the 7 periods).
Policies
Late Policy
Sickness, Health Policy
Absence(s) in Class and in Lab
Honor Code
Contact
- Talk to me in lab, 1220 LBME, I’ll be there a lot and am at your disposal;
- Stop by my office, 2130 LBME, if I’m in my office, I will almost always talk to you;
- Call my office phone, 734-647-8638, if I’m in my office, I will almost always answer it;
- Talk to me before or after class or in the hallway, but make sure I write it down;
- Send me an email to my email address, belmont@umich.edu (within 3-5 business days).
New and Experimental Features
Readings
Interviews
Reviews and Reflections
Readings by source
- Abdel-Aleem, Salah., “The design and management of medical device clinical trials strategies and challenges.” John Wiley, 2010
- 1. Challenges to the Design of Clinical Study
- 4. Fraud and Misconduct in Clinical Trials
- 5. Challenges to the Regulation of Medical Device
- 6. Challenges of Global Clinical Studies and the CE Mark Process
- 8. Bioethics in Clinical Research
- Baura, Gail D., “Medical device technologies a systems based overview using engineering standards.” Elsevier/Academic Press, 2012.
- Chapter 1. Diagnosis and Therapy
- Chapter 2. Electrocardiographs
- Chapter 9. Hemodialysis Delivery Systems
- Chapter 11. Pulse Oximeters
- Fries, Richard C., “Reliable design of medical devices.” CRC Press, 2013.
- Chapter 7. The FDA
- Chapter 12. Liability
- Chapter 13. Intellectual Property
- Chapter 32. Transfer to Manufacturing
- Chapter 33. Hardware Manufacturing
- V. Gavrishchaka, O. Senyukova and M. Koepke (2019) “Synergy of physics-based reasoning and machine learning in biomedical applications: towards unlimited deep learning with limited data”, Advances in Physics: X, 4:1
- Kaniusas, Eugenijus., “Biomedical Signals and Sensors I: Linking Physiological Phenomena and Biosignals.” Springer, 2012.
- 2.2. Neurons and Receptors
- 2.4. Heart
- 2.5. Circulatory System
- 2.6. Respiratory System
- 3.1. Vital Phenomena and Their Parameters
- 3.2. Parameter Behavior
- Kendler, Jonathan. and Strochlic, Allison Y., “Usability testing of medical devices.” CRC Press, Taylor & Francis Group, 2016.
- Chapter 3. The Commercial Imperative
- Chapter 4. Testing Costs
- Chapter 7. Writing a Test Plan
- Chapter 12. Conducting the Test
- Chapter 16. Reporting Results
- Kucklick, Theodore R., “The medical device R&D handbook.” CRC press, Taylor & Francis Group, 2013.
- 12. Clinical Observation: How to Be Welcome (or at Least Tolerated) in the Operating Room and Laboratory
- 14. Intellectual Property Strategy for Med-Tech Start-Ups
- 15. Regulatory Affairs: Medical Device
- 17. Brief Introduction to Preclinical Research
- 24. Interview with J. Casey McGlynn
- 25. Keys to Creating Value for Early Stage Medical Device Companies
- 27. Medical Device Sales 101
- 29. How to Fail as an Entrepreneur
- Liang, Hualou., Bronzino, Joseph D., and Peterson, Donald R., “Biosignal processing principles and practices.” CRC Press/Taylor & Francis, 2013.
- 1. Digital Biomedical Signal Acquisition and Processing
- 2. Time–Frequency Signal Representations for Biomedical Signals
- Medical Device Amendments of 1976. Public Law 94-295, 94th U.S. Congress.
- “Medicare-for-All”. H.R. 1384 and S. 1129, 116th U.S. Congress
- Northrop, Robert B., “Noninvasive instrumentation and measurement in medical diagnosis.” CRC Press, Taylor & Francis Group, 2018.
- 4. Measurement of Electrical Potentials and Magnetic Fields from the Body Surface
- Plethysmography
- Pulmonary Function Tests
- Prutchi, David and Norris, Michael, “Design and development of medical electronic instrumentation a practical perspective of the design, construction, and test of medical devices.” Wiley-Interscience, 2005.
- 1. Biopotential amplifiers
- 2. Bandpass selection for biopotential amplifiers
- 3. Design of safe medical device prototypes
- 4. Electromagnetic compatibility and medical devices
- 5. Signal conditioning, data acquisition, and spectral analysis
- J. Rajeswari and M. Jagannath, “Advances in biomedical signal and image processing – A system review”, Informatics in Medicine Unlocked 8 (2017) 13–19
- Riegel v. Medtronic, Inc., 552 U. S. 312 (2008)
- Semmlow, John L., “Circuits, signals and systems for bioengineers : a MATLAB-based introduction.” Academic Press, 2018.
- Chapter 1. The Big Picture: Bioengineering Signals and Systems
- Chapter 2. Signal Analysis in the Time Domain
- Chapter 3. Signal Analysis in the Frequency Domain: The Fourier Series and the Fourier Transformation
- Chapter 4. Signal Analysis in the Frequency Domain—Implications and Applications
- Chapter 13. Analysis of Analog Circuits and Models
- Chapter 15. Basic Analog Electronics: Operational Amplifiers
- K. Shameer, K. W. Johnson, B.S. Glicksberg, et al. “Machine learning in cardiovascular medicine: are we there yet?”, Heart 2018;104:1156–1164.
- G. A. Van Norman, “Drugs and Devices: Comparison of European and U.S. Approval Processes”, JACC: Basic to Translational Science, Volume 1, Issue 5, 2016, 399-412
- Webster, John G., and Eren, Halit, “Measurement, instrumentation, and sensors handbook electromagnetic, optical, radiation, chemical, and biomedical measurement.” CRC Press, Taylor & Francis Group, 2014.
- 19. Oscilloscope Voltage Measurement
- 41. Time Measurement
- 42. Frequency Measurement
- 65. Blood Pressure Measurement
- 68. Blood Chemistry Measurement
- M. Wacker and H. Witte, “Time-frequency Techniques in Biomedical Signal Analysis: A Tutorial Review of Similarities and Differences”, Methods Inf Med 2013; 52: 279–296
- Wood, Andrew W., “Physiology, biophysics, and biomedical engineering.” CRC Press, 2012.
- 2. Fundamentals of Electrical Circuits for Biomedicine
- 8. Cardiac Biophysics
- 10. The Vascular System: Blood Flow Patterns in Various Parts of the Circulation
- 11. Cardiovascular System Monitoring
- 12. Respiratory Biophysics
- 13. Renal Biophysics and Dialysis
- 16. The Biophysics of Sensation—General
- 20. Physiological Signal Processing
- Physiological Modeling
- World Health Organization (WHO), “Medical devices: managing the mismatch : an outcome of the Priority Medical Devices project.” Geneva, 2010.
Readings in order
Their names
Frédéric Boisseau, 42, building maintenance worker
Franck Brinsolaro, 49, police officer
Jean Cabut, “Cabu”, 76, cartoonist
Elsa Cayat, 54, psychoanalyst and columnist
Stéphane Charbonnier, “Charb”, 47, cartoonist, columnist, and director of publication
Philippe Honoré, 73, cartoonist
Bernard Maris, 68, economist, editor, and columnist
Ahmed Merabet, 42, police officer
Mustapha Ourrad, 60, copy editor
Michel Renaud, 69, a travel writer and festival organizer
Bernard Verlhac, “Tignous”, 57, cartoonist
Georges Wolinski, 80, cartoonist